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AGNP BOARD EXAM QUESTIONS Orthopedics Prescribing (103 Questions)

1. Which medication is NOT a brand name for acetaminophen?
2. To treat low back pain in a patient for whom nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated, the recommended therapy is:
3. The patient at highest risk for side effects from cyclobenzaprine (Amrix) is a:
4. When assessing a patient with suspected acetaminophen (Tylenol) overdose, the time of ingestion can be confirmed by checking:
5. A patient with severe osteoarthritis is complaining of a pain exacerbation due to weather change. Ketorolac should be avoided in this patient due to a drug-drug interaction with:
6. The half-life elimination of colchicine (Colcrys), used in the treatment of gout, is approximately:
7. Dantrolene (Dantrium) reduces skeletal muscle spasticity by:
8. Which formulation of naproxen would result in fewer GI side effects?
9. Salicylates, such as aspirin,:
10. When evaluating the effectiveness of baclofen (Lioresal), the LEAST appropriate goal is to:
11. The concomitant use of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) can cause:
12. Clindamycin (Cleocin) is NOT indicated for the treatment of serious infections, such as septic arthritis, caused by:
13. Intra-articular steroid injections are NOT contraindicated:
14. Patients should be instructed to take tizanidine (Zanaflex):
15. Before prescribing Dantrolene (Dantrium), a peripherally-acting muscle relaxant, obtain a baseline serum:
16. The brand name for cyclobenzaprine is:
17. The intra-articular steroid with the longest duration of action is:
18. Ketorolac (Toradol), administered intramuscularly, would be indicated for the patient with a complaint of:
19. Dosing of acetaminophen (Tylenol) in children weighing less than 50 kg is:
20. The maximum FDA-recommended single dose of oral acetaminophen (Tylenol) in an adult is:
21. Which medication would NOT be appropriate for the treatment of acute gout?
22. A 42-year-old woman was started on naproxen sodium (Aleve) for the treatment of tendinitis in the right ankle. The patient calls 3 days later and reports swelling in both ankles. The nurse practitioner should advise the patient to:
23. Oral ketorolac (Toradol) should not be taken for more than:
24. Which medication minimizes bone loss, decreasing the risk for osteoporosis?
25. In adults with normal renal function, the half-life elimination of naproxen sodium (Aleve) is approximately:
26. Which diagnosis is NOT a contraindication to nonsteroidal anti-inflammatory agents?
27. Which adverse event is NOT related to colchicine?
28. The recommended antidote for acetaminophen toxicity is:
29. Symptoms of salicylate (i.e., aspirin) poisoning may include:
30. The brand name for tizanidine is:
31. Caution is advised with concomitant use of salicylates and:
32. Baclofen (Lioresal), used in the treatment of spondylosis, may be administered:
33. Patients should be advised to avoid combining tizanidine (Zanaflex) with:
34. Patients should be instructed to avoid abrupt withdrawal of baclofen (Lioresal) to prevent the occurrence of:
35. The generic name of Toradol, a nonsteroidal anti-inflammatory drug, is:
36. NSAIDs should be used with caution in the patient who has:
37. Raloxifene (Evista) is indicated for the treatment of osteoporosis. It also:
38. Which amount of calcium and vitamin D does the National Osteoporosis Foundation recommend to prevent osteoporosis in women 50 years and older?
39. The concomitant use of tizanidine (Zanaflex) and other drugs that inhibit the CYP1A2 enzyme pathway is absolutely contraindicated. Other CYP1A2 inhibitors include:
40. The drug of choice for analgesic and antipyretic use during pregnancy is:
41. For patients taking tizanidine (Zanaflex), diagnostic testing at baseline and when maximum dose is achieved includes:
42. The brand name of dantrolene, a skeletal muscle relaxant, is:
43. When treating a fracture, factors that influence acetaminophen (Tylenol) toxicity do NOT include:
44. A commonly reported side effect of tizanidine (Zanaflex), a skeletal muscle relaxant, is:
45. The recommended interval between subacromial intra-articular steroid injections is:
46. A potential side effect related to the use of ketorolac (Toradol) is:
47. Ketorolac (Toradol), a nonsteroidal antiinflammatory drug, reduces pain by:
48. Two black box warnings for ibuprofen (Motrin) include increased risk for:
49. When corticosteroids are used in combination with nonsteroidal anti-inflammatory drugs (NSAIDs), patients may develop:
50. Naproxen (Aleve) is NOT indicated for relief of signs and symptoms associated with:
51. In a 50-year-old nondiabetic man with moderate inflammation secondary to septic bursitis, the most appropriate therapy is:
52. Ketorolac (Toradol), a nonsteroidal anti-inflammatory drug, is:
53. Allopurinol (Zyloprim) is NOT indicated for the treatment of:
54. The risk for gastrointestinal bleeding may increase with concomitant use of ibuprofen (Motrin) and:
55. Patients who have difficulty swallowing tizanidine (Zanaflex) capsules should be:
56. Cyclobenzaprine (Fexmid) should not be administered concomitantly with:
57. Colchicine (Colcrys) is an alkaloid that is:
58. The maximum recommended daily dose of acetaminophen (Tylenol) for the management of pain associated with a clavicular fracture is:
59. Baclofen (Lioresal), a centrally-acting muscle relaxant, is indicated for the treatment of:
60. The generic name for Advil, sometimes used in the treatment of joint pain, is:
61. Initial monotherapy for the treatment of low back pain is:
62. Which muscle relaxant is monitored by the Drug Enforcement Agency and is listed as a Schedule IV medication?
63. When administering allopurinol (Zyloprim) for the treatment of gout, it is important to instruct the patient to:
64. Probenecid, used in the treatment of gout, works by:
65. The medication initially recommended to control pain associated with non-inflammatory osteoarthritis is:
66. Brand names for naproxen, a nonsteroidal anti-inflammatory drug, do NOT include:
67. Which medication helps the kidneys excrete uric acid?
68. Corticosteroids, sometimes prescribed to reduce inflammation related to rheumatoid arthritis, should NOT be given in combination with:
69. Which of the following is NOT classified as a muscle relaxant:
70. The use of carisoprodol (Soma) should be limited to 2-3 weeks, mostly due to the potential for:
71. Clindamycin (Cleocin) is indicated for the treatment of serious infections of:
72. Which of the following is NOT a reason to discontinue allopurinol (Zyloprim)?
73. Prior to initiating pharmacologic therapy for the treatment of osteoporosis, the nurse practitioner should evaluate baseline serum:
74. The term systemic corticosteroids refers to corticosteroids that are:
75. Acetaminophen (Tylenol) works to reduce pain by:
76. Patients who are taking bisphosphonates (i.e., alendronate [Fosamax]) for osteoporosis should be advised to:
77. Ketorolac (Toradol), for the treatment of moderate pain, is classified as a(n):
78. Allopurinol (Zyloprim), used in the treatment of gout, decreases serum uric acid by:
79. Acetaminophen (Tylenol) is contraindicated in patients who have:
80. Cyclobenzaprine (Fexmid), a skeletal muscle relaxant, should not be taken consistently for more than:
81. Ibandronate (Boniva), a biphosphonate, is approved for:
82. The generic name for Indocin, used in the treatment of gout, is:
83. Baclofen (Lioresal), a centrally-acting muscle relaxant, is indicated for the treatment of symptoms related to:
84. The most common adverse reaction to cyclobenzaprine (Fexmid) is:
85. The onset of analgesic action of naproxen sodium (Aleve) occurs within:
86. Bisphosphonates, used in the treatment of osteoporosis,:
87. The most significant adverse reaction associated with the overuse of acetaminophen (Tylenol) is:
88. Acetaminophen (Tylenol) for the treatment of osteoarthritic pain is classified as a(n):
89. The generic name for Lioresal is:
90. Acetaminophen (Tylenol) does NOT produce:
91. The mechanism of action of NSAIDs is to:
92. The maximum daily dose of ibuprofen (Motrin), sometimes used for relief of moderate low back pain, is:
93. Cyclobenzaprine (Fexmid) and tizanidine (Zanaflex) are classified as:
94. The generic name for Robaxin is:
95. Cyclobenzaprine (Fexmid), a skeletal muscle relaxant, is indicated in the treatment of:
96. Patients taking acetaminophen (Tylenol) should be advised to avoid:
97. The most common side effect associated with ketorolac (Toradol) for the treatment of moderate musculoskeletal pain is:
98. Caution is advised with the concomitant administration of angiotensin-converting enzyme (ACE) inhibitors and nonsteroidal antiinflammatory drugs (NSAIDs) because:
99. NSAIDs potentiate the effects of ACE inhibitors, causing hypotension.  
100. The best initial medication for the treatment of acute gout in the great toe of a patient with a creatinine clearance of 50 mL/min is:
101. Glucocorticoids, sometimes used to treat rheumatoid arthritis,:
102. The generic name for Soma is:
103. A nonsteroidal anti-inflammatory drug (NSAID) that can be administered orally and intramuscularly is:
104. Oral ibuprofen (Motrin) has a bioavailability of: